Rosemary M Gibson Selected Research

VRT 018858

10/2007

A selective, non-peptide caspase-1 inhibitor, VRT-018858, markedly reduces brain damage induced by transient ischemia in the rat.

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Rosemary M Gibson Research Topics

Disease

2	Central Nervous System Diseases (CNS Diseases) 07/2006 - 01/2006
2	Inflammation (Inflammations) 01/2006 - 11/2004
1	Ischemia 10/2007
1	Parkinson Disease (Parkinson's Disease) 05/2007
1	Stroke (Strokes) 01/2006
1	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2006
1	Alzheimer Disease (Alzheimer's Disease) 01/2006
1	Rheumatoid Arthritis 01/2006
1	Infections 01/2006
1	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2004

Drug/Important Bio-Agent (IBA)

2	Interleukin-1 (Interleukin 1)IBA 07/2006 - 11/2004
2	Free RadicalsIBA 07/2006 - 01/2006
2	CytokinesIBA 01/2006 - 11/2004
1	interleukin-1beta-converting enzyme inhibitorIBA 10/2007
1	VRT 018858IBA 10/2007
1	Peptides (Polypeptides)IBA 10/2007
1	LipidsIBA 05/2007
1	CeramidesIBA 05/2007
1	CaspasesIBA 07/2006
1	Anti-Inflammatory Agents (Anti-Inflammatories)IBA 01/2006
1	Complement System Proteins (Complement)IBA 01/2006
1	InterleukinsIBA 01/2006
1	ProstaglandinsIBA 01/2006
1	Cyclooxygenase InhibitorsIBA 01/2006
1	ChemokinesIBA 01/2006

Therapy/Procedure

1	Therapeutics 01/2006